ea0004oc1 | Growth regulation and development | SFE2002
Korur N
, Pearce S
, Dandrea J
, Ingleton P
, Symonds M
, Stephenson T
Introduction: Mice in which the prolactin receptor (PRLR) gene is knocked out have reduced adipose tissue in later life. Abundance of the PRLR is greatest in adipose tissue at birth and is reduced following placental restriction. The present study investigated the impact of maternal nutrient restriction over the final two months of gestation on PRLR abundance in developing lambs.Methods: Eighteen multiparous twin bearing ewes were entered into the study,...